Друг дружке- не мешают

[chuka_lis]

Австралийцы обратили внимание на 2 случая  (это не значит что их всего 2,  просто  их "словили" в ходе скрининга), когда у людей был ковид от 2 штаммов коронавиурса  сразу. В респираторной системе двоих больных (не только коронавирусом, а и вообще- у обоих проблемы с почками, сердцем, диабет 2 типа, итп), никак не связанных друг с другом, одновременно присутстовали и дельта, и омикрон. Обое были симптоматичными (ОРВИ). Один из больных был привит двумя дозами вакцины файзер, второй - непривитый по личному выбору.
Никаких других типичных  вирусов "простуды" у пациентов не обнаружили.
 Авторы статьи подчеркивают важность  генетического мониторинга курсирующих вирусов.
А я думаю, еще, что  это "намек" на возможности рекомбинации и появления новых штаммов, в которых мутации  будут группироваться.
We identified the co-infection of the SARS-CoV-2 Omicron and Delta variants in two epidemiologically unrelated patients with chronic kidney disease requiring haemodialysis. Both SARS-CoV-2 variants were co-circulating locally at the time of detection. Amplicon- and probe-based sequencing using short- and long-read technologies identified and quantified Omicron and Delta subpopulations in respiratory samples from the two patients. These findings highlight the importance of genomic surveillance in vulnerable populations.
Neither patient had prior evidence of COVID-19 infection. Case A had received two doses of the COMIRNATY® (Pfizer) vaccine with the second dose ten weeks prior to diagnosis. Case B remained unvaccinated by choice.PCR did not detect human influenza viruses A or B, respiratory syncytial virus, parainfluenza viruses 1, 2, and 3, human metapneumovirus or rhinovirus in samples from both cases.
Population analysis of genomic data generated using RVOP methods estimated that the VOC proportions in samples from Case A were 21% Omicron and 77% Delta on Day 2, compared to 45% Omicron and 53% Delta on Day 3. Samples from Case B contained 42% Omicron and 53% Delta on Day 3, and 11% Omicron and 84% Delta on Day 11. Despite the same pattern of mixed infection, the two cases were not genomically linked in a transmission pathway (Figure 2B). The two Omicron sequences were distinct representatives of the Omicron (sub-lineage BA.1) strain currently predominating in Sydney, while the two Delta sequences belonged to different genomic clusters of Delta (sub-lineage AY.39.1) also circulating locally. Although these findings confirm phylogenetically distinct and epidemiologically relevant SARS-CoV-2 variants in both cases, they are not sufficient to conclude whether these cases acquired their dual SARS-CoV-2 co-infection following sequential exposures to individuals with a single lineage infection. The recognition of mixed infections may also affect the selection of appropriate antiviral therapy and infection control measures.